Sodium orthovanadate (Na3VO4)-Granules introduce:
Sodium orthovanadate is the inorganic compound with the chemical formula Na3VO4·2H2O (sodium orthovanadate dihydrate). It is a colorless, water-soluble solid.
Molar mass:183.908 g/mol
Density:2.16 g/cm3, solid
Melting point:858 °C (1,576 °F; 1,131 K)
Solubility in water:22.17 g/100 mL
Solubility:insoluble in ethanol
Inhibitor of protein tyrosine phosphatase and alkaline phosphate Sodium orthovanadate is used in protein analysis in molecular biology and acts as an inhibitor of protein tyrosine phosphatases, alkaline phosphatases and kinases. It is also used to prepare the stop solution in dephosphorylation assay of insulin receptor kinase. It serves as a reagent in the development of matrix Chip that utilizes surface-immobilized antibodies. Further, it is utilized for the preservation of protein tyrosyl phosphorylation state in cells and cell lysates.
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